Differential hormonal profiles of adrenomedullin and proadrenomedullin n-terminal 20 peptide in patients with heart failure and effect of treatment on their plasma levels

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The effect of adrenomedullin and proadrenomedullin N- terminal 20 peptide on angiotensin II induced vascular smooth muscle cell proliferation

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the effect of adrenomedullin and proadrenomedullin n- terminal 20 peptide on angiotensin ii induced vascular smooth muscle cell proliferation

objective(s): the study aimed to investigate the effects of adrenomedullin (adm) and proadrenomedullin n- terminal 20 peptide (pamp) on angiotensin ii (angii)-stimulated proliferation in vascular smooth muscle cells (vsmcs). materials and methods: thoracic aorta was obtained from wistar rats and vsmcs were isolated from aorta tissues and then cultured. in vitro cultured vsmcs were stimulated wi...

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Expression of adrenomedullin and proadrenomedullin N-terminal 20 peptide in human and rat prostate.

Adrenomedullin (AM) and proadrenomedullin N-terminal 20 peptide (PAMP) are two recently discovered hypotensive peptides translated from the same message transcript (preproAM mRNA). In this article we report the presence of AM, PAMP, and their mRNA in human and rat prostate and of AM receptor mRNA in rat prostate. PreproAM mRNA was found in the epithelium of normal human and rat prostate glands ...

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Adrenomedullin and proadrenomedullin N-terminal 20 peptide in the normal prostate and in prostate carcinoma.

There is increasing evidence for the important role played by regulatory peptides in the physiology of the normal and neoplastic prostate. Adrenomedullin (AM) and pro-adrenomedullin N-terminal 20 peptide (PAMP) are recently discovered regulatory peptides widely expressed in the normal prostate and in prostate carcinoma. AM is produced in secretory, stroma, and endothelial cells and in neurons o...

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ژورنال

عنوان ژورنال: Clinical Cardiology

سال: 1999

ISSN: 0160-9289,1932-8737

DOI: 10.1002/clc.4960220211